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Fundamentals of Disease & Treatment HyprPaper – 3

September 26, 2020

WELCOME TO YOUR FUNDAMENTALS OF DISEASE & TREATMENT HYPRPAPER!

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Question 1 of 48

1. Question
Which of the following is a feature of benign tumors?
- Local infiltration
- Expansile growth pattern
- High mitotic index
- Nuclear pleomorphism
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Question 2 of 48

2. Question
In which of the following areas of the stimulated lymph node are the B cells predominantly found?
- Germinal center
- Primary follicle
- Paracortex
- Outer cortex
Correct

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Question 3 of 48

3. Question
Which of the following active proteolytic fragments are the most active anaphylatoxins?
- C2a
- C3a
- C4a
- C5a
Correct

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Question 4 of 48

4. Question
Normal enlargement of the prostate gland that occurs with increasing age is most likely due to:
- A. Hypertrophy
- B. Hyperplasia
- C. Anaplasia
- D. Dysplasia
Correct

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Question 5 of 48

5. Question
What is the family name for virus?
- A. Viridae
- B. Viriales
- C. Virinae
- D. Virion
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Question 6 of 48

6. Question
A child gets stuck with a rusty nail. The wound was cleaned and covered with gauze. What is the first step of healing of the wound?
- A. Activation of inflammatory cells
- B. Formation of Fibrin clot
- C. Activation of B lymphocytes
- D. Activation of T lymphocytes
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Question 7 of 48

7. Question
What is the function of a bacteria’s capsule?
- A. Protection against invasion
- B. Protection against phagocytosis
- C. Protection against detection
- D. Protection against antibodies
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Question 8 of 48

8. Question
What is the function of fimbriae?
- A. Adherence
- B. Motility
- C. Conjugation
- D. Penetration
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Question 9 of 48

9. Question
Main component of bacterial cell wall:
- A. Mucopeptide
- B. Glycoprotein
- C. Glycolipid
- D. Peptidoglycans
Correct

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Question 10 of 48

10. Question
The term obligate anaerobes means
- Bacteria that are poisoned by oxygen
- Bacteria that can tolerate low oxygen concentrations
- Can survive with or without oxygen
- Require oxygen to survive
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Question 11 of 48

11. Question
Which of the following media is not used for cultivating fungus?
- Blood agar
- Sabouraud dextrose
- Malt extract
- Brain heart infusion medium
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Question 12 of 48

12. Question
To which of the following classes does Cryptococcus belong?
- Ascomycota
- Tremellomycetes
- Oomycete
- Zygomycota
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Question 13 of 48

13. Question
G proteins are related to what kind of receptor?
- Endotropic
- Metabotropic
- Tyrosine kinase
- Gene transcription regulators
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Question 14 of 48

14. Question
Which of the following about lymph nodes which is correct?
- B cells are found in the cortex
- B cells are found in interfollicular space
- T cells are found in periarteriolar space
- B cells are found in the hilum
Correct

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Question 15 of 48

15. Question
Which statement concerning the spleen is incorrect?
- Expand into the left inguinal space
- Has dimensions 1 x 3 x 5 inches
- Between the 9 – 11 left ribs
- Parallel to rib 10
Correct

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Question 16 of 48

16. Question
Which statement is true concerning the reaction of an agonist in the presence of competitive antagonists?
- Shift the dose-response curve to the left
- Shift the dose response curve to the right
- Has no effect on the dose-response curve
- Dose-response curves show no proportionality with the introduction of the antagonist
Correct

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Question 17 of 48

17. Question
Which form of antagonism is due to mediator exhaustion?
- chemical
- pharmacological
- physiological
- tachyphylaxis
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Question 18 of 48

18. Question
Which form of drug administration most likely leads to toxicity?
- A. sublingual
- B. intravenous
- C. cutaneous
- D. rectal
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Question 19 of 48

19. Question
Which of the following will have a deleterious effect on bioavailability?
- Decreased first pass metabolism
- Decreased energy-dependent efflux
- Increased rate of absorption
- Increased presences of CYP450 isozymes
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Question 20 of 48

20. Question
Which of the following statements is true?
- Preferential binding reduces drug distribution
- All drugs are equally distributed in the body
- Enterohepatic circulation reduces the length of time in the body
- Intrathecal administration is an example of administration via the enteral route
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Question 21 of 48

21. Question
Which is not true?
- A. P450 enzymes operate in phase two of drug metabolism
- B. Glucuronidation is an example of a phase 2 reaction
- C. P450 enzymes carry out oxidation
- D. Phenobarbital induces P450 activity
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Question 22 of 48

22. Question
Which term refers to single-cell death caused by cellular injury due to hormones and genes?
- A. necrosis
- B. fatty change
- C. apoptosis
- D. degradation
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Question 23 of 48

23. Question
Which form of necrosis is seen in heart tissue?
- A. coagulative
- B. liquefactive
- C. caseous
- D. granuloma
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Question 24 of 48

24. Question
Which is the hall mark of cell death?
- A. Deposition of calcium
- B. Deposition of sodium
- C. Increase in intracellular sodium
- D. The expulsion of genetic material from the cell
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Question 25 of 48

25. Question
Which statement is true?
- A. During negative selection in the thymus gland most T cells that bind too easily to self antigens are kept alive.
- B. During the secondary antibody response, IgM antibodies are the most abundant
- C. The fragment crystallizable region (Fc region) is the tail region of an antibody that interacts with cell surface receptors
- D. During the intermediary antibody response, IgM antibodies are abundant
Correct

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Question 26 of 48

26. Question
Swelling in Johnny’s knee after he ‘bucked’ it is most like due to:
- A. Increased vascular permeability
- B. Vasoconstriction
- C. Inflammatory cells
- D. Cellulitis
Correct

Incorrect
Question 27 of 48

27. Question
Which of the following statements regarding osteomyelitis is false?
- A. The long bones of the arms and legs are most commonly involved in children
- B. The feet, spine, and hips are most commonly involved in adults.
- C. Sometimes caused by a fungal infection
- D. Rarely caused by Staphylococcus bacteria.
Correct

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Question 28 of 48

28. Question
Sue has hookworms. Besides neutrophils, what other cell is prominent?
- A. Lymphocytes
- B. Macrophages
- C. Basophils
- D. Eosinophils
Correct

Incorrect
Question 29 of 48

29. Question
Which statement about granulomas is true?
- A. It shows a specific form of chronic inflammation
- B. It is seen in granulomatous tissue
- C. A collection of B-lymphocytes
- D. A collection of T-lymphocytes
Correct

Incorrect
Question 30 of 48

30. Question
Which is true about sarcoidosis?
- A. multiorgan involvement
- B. is a caseous necrosis
- C. involves hypocalcemia
- D. involves the production of granulation tissue
Correct

Incorrect
Question 31 of 48

31. Question
Growth in prostate in older men is an example of
- A. hypertrophy
- B. hyperplasia
- C. aplasia
- D. hypoplasia
Correct

Incorrect
Question 32 of 48

32. Question
A baby born with tiny lungs is an example of
- A. agenesis
- B. aplasia
- C. hypoplasia
- D. atrophy
Correct

Incorrect
Question 33 of 48

33. Question
Metaplasia is characterised by
- A. atypia of epithelium
- B. hyperchromasia
- C. pleomorphic cells
- D. anaplasia
Correct

Incorrect
Question 34 of 48

34. Question
Which of the following is normally benign?
- A. melanoma
- B. hepatoma
- C. lymphoma
- D. meningioma
Correct

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Question 35 of 48

35. Question
Normal tissue at abnormal site defines:
- A. Choristoma
- B. Hamartoma
- C. Teratoma
- D. Metaplasia
Correct

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Question 36 of 48

36. Question
Stage of a malignant tumour is dependent on which parameter?
- A. Size of secondary tumour
- B. Extent of spread
- C. Presence of metaplasia
- D. Extent of angiogenesis
Correct

Incorrect
Question 37 of 48

37. Question
Krukenberg tumour spreads from ovarian tissue to stomach by which of the following?
- A. Lymphatic drainage
- B. Haematogenous
- C. Transcoelomic
- D. Cross-contamination
Correct

Incorrect
Question 38 of 48

38. Question
Which is an oncogene?
- A. Ras
- B. Rb1
- C. p53
- D. NF1
Correct

Incorrect
Question 39 of 48

39. Question
Which of the following drugs is metabolized to the toxic agent Acrolein?
- A. busulfan
- B. cyclophosphamide
- C. mercaptopurine
- D. cisplatin
Correct

Incorrect
Question 40 of 48

40. Question
Cytarabine is mainly sued to treat which of the following?
- Lymphomas
- Melanoma
- Leukemias
- Sarcoma
Correct

Incorrect
Question 41 of 48

41. Question
Administration of chemotherapy before surgery is referred to as:
- A. palliative
- B. neoadjuvant
- C. adjuvant
- D. dense
Correct

Incorrect
Question 42 of 48

42. Question
Which statement about the plasma protein albumin is true?
- A. 65 – 70 Daltons
- B. accounts for less than half of all plasma proteins
- C. high contribution to osmolality
- D. oedema occurs as a result of a concentration higher than 25g/l
Correct

Incorrect
Question 43 of 48

43. Question
Which is true?
- A. Ceruloplasmin transports copper
- B. The level of iron is increased in acute phase response
- C. Erythropoietin transports iron to the bone marrow
- D. Iron is a vital component of hormones
Correct

Incorrect
Question 44 of 48

44. Question
Which of the following statements regarding immunoglobulins which is true?
- A. Each individual immunoglobulin has equal kappa and lambda units
- B. IgA is the largest
- C. IgE carries out type I hypersensitivity
- D. IgG has high titre in primary response
Correct

Incorrect
Question 45 of 48

45. Question
Monoclonal gammopathy is associated with which of the following pathologies?
- A. chronic liver disease
- B. chronic vascular infections
- C. diabetes mellitus
- D. lymphocytic leukemia
Correct

Incorrect
Question 46 of 48

46. Question
Which does not have an effect on bacterial cell wall synthesis?
- A. penicillin
- B. oxacillin
- C. rifampicin
- D. vancomycin
Correct

Incorrect
Question 47 of 48

47. Question
Which of the following drugs is used to treat colon cancer?
- A. Cyclophosphamide
- B. Ondansetron
- C. Levamisole
- D. Methotrexate
Correct

Incorrect
Question 48 of 48

48. Question
Which of the following is penicillinase-resistant?
- A. Benzylpenicillin G
- B. Amoxicillin
- C. Ampicillin
- D. Nafcillin
Correct

Incorrect

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Fundamentals of Disease & Treatment HyprPaper – 3

September 26, 2020

WELCOME TO YOUR FUNDAMENTALS OF DISEASE & TREATMENT HYPRPAPER!

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