Endocrine & Skin HyprPaper – 4

A pattern of inflammation of the skin characterized clinically in the acute stage by ill-defined groups of erythematous vesicles and/or papules and in the chronic stage by scaling and lichenification.

Which statement is incorrect about atopic dermatitis?

A 3 year old female presents with symmetrical well-defined, erythematous (red) plaques covered by thick silvery scales on the lower back and extensor aspects of the elbow. A consultant dermatologist observes that the patient exhibits the ‘koebner phenomenon.’ What was the most likely diagnosis?

A serious autoimmune disorder of intraepidermal cell cohesion, resulting in flaccid blisters and painful erosions of the skin and mucous membranes. Erosions do not heal spontaneously.

A 46-year-old jewish man presented with a generalized, blistering rash of 4 weeks’ duration. His trunk and forearm was mainly affected. On examination, there was extensive blistering and large areas of denuded skin (Nikolskys sign). Ulcers were also present in his mouth. Immunofluoresence showed linear deposits of IgG. This person was diagnosed with:

The gold standard of diagnosing adrenal insufficiency:

Which is an immediate lateral relation to the hypothalamus?

The regulation of water balance and production of vasopressin and oxytocin involves which nucleus of the thalamus?

Which nucleus of the thalamus stimulates parasympathetic nervous system and thermal regulation/ destruction of which nucleus results in hyperthermia?

Which nucleus of the thalamus is involved with sexual dimorphism/release of gonadotrophin?

Which nucleus receives input from the retina/ controls circadian rhythm?

In Wernicke’s encephalopathy hemorrhagic lesions are located in:

Stimulation of the dorso-medial nucleus would result in:

Which nucleus of the thalamus produces hypothalamic releasing factors?

Destruction of the ventromedial nucleus results in:

Destruction of the lateral nucleus results in

Major afferents to the hypothalamus include all of the following except:

Major efferents from the hypothalamus include all of the following except:

Which is an immediate posterior relation of the hypothalamus?

Blood to the cavernous sinus drains from all the following except:

Which is false about the thyroid gland?

Crucial relation to the medial surface of the lateral lobe is the:

The parafollicular cells of the thyroid gland are derived from:

Most dominant microorganism in impetigo is:

“Yaws” is caused by the organism:

Pitiriasis versicalor is caused by:

The diagnosis of Pitiriasis versicalor is usually made by:

Which microorganism commonly affects the skin and hair but not the nails?

Destruction of the pineal gland may cause:

In the normal individual cortisol secretion increased by all the following except:

The hormone receptors for thyroxine are located in the:

Delta cells of the pancreas secrete which hormone?

The following substances peak during sleep VS. When awake except:

Which of the following is false about growth hormone secretion?

Which statement is false about Triiodothyronine?

Highly elevated concentration thyroid hormones cause all the following except:

The following stimulates secretion of blood glucagon except:

The most common cause of conns syndrome is:

Hurthle cells is a common feature associated with:

Most of the cortisol in plasma is bound to:

What is the most common cause of hyperpituitarism?

In Addison’s disease, a person may have all the following except:

A 28-year-old woman has had difficulty concentrating on her job at work for the past month. She is constantly getting up and walking around to visit co-workers. She complains that the work area is too hot. She seems nervous and spills her coffee a lot. She has been eating more but has lost 5 kg in the past month. On physical examination, her temperature is 37.5 C, pulse 101/minute, respiratory rate 18/minute, and blood pressure 145/85 mm Hg. All of the following would be expected except?

Which of the following is a usual characteristic of diabetes type 1?

The following are possible side effects of glucocorticoids effects except:

Treatment of hypothalamic pituitary malfunction involves which combination of drugs?

Which drug gives disulfiram-like action?

Which drug combination gives significant improvement in glycemic control?

Regarding hypothalamic control of the pituitary function:

A chronic inflammatory disorder affecting the pilosebaceous unit which is characterized by the formation of comedones, erythematous papules and pustules.